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* **Fluorescence In Situ Hybridization (FISH)**: This is a more sensitive test that looks at the HER2 gene itself. It counts how many copies of the gene are present in the cancer cells. If there aren't too many copies, then the cancer is considered HER2-negative. This test is used when the IHC result is unclear (2+). It’s also used to confirm HER2 status. The FISH test gives a more definitive answer.
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